Company Overview: Agile Smart Health Technology is a global leader in providing high-quality and purity herbal extracts and APIs for the pharmaceutical, food, and cosmetic industries.
Product Range: Showcase crocin, saffron extract, curcumin, berberine, thymol, menthol, concrete, and absolute with their benefits and applications.
Quality Assurance: Emphasize GMP-certified facilities, rigorous quality control, and third-party testing.
- Crocin (Pure Saffron Extract)
• Description: Crocin, derived from saffron, is a powerful natural compound known for its antioxidant, anti-inflammatory, and neuroprotective properties. With its vibrant yellow hue and therapeutic benefits, crocin is ideal for pharmaceutical, nutraceutical, and cosmetic applications.
• Key Applications:
o Functional foods and beverages.
o Anti-depressant and cognitive-enhancement supplements.
o Natural skin care formulations. - Saffron Extract
• Description: Premium saffron extract, standardized for high crocin and safranal content, delivers potent antioxidant and anti-inflammatory benefits. This extract enhances both flavor and health benefits in pharmaceutical and functional products.
• Key Applications:
o Mood enhancement and stress relief supplements.
o High-end cosmetic formulations.
o Luxury food and beverage flavoring. - Curcumin (Turmeric Extract)
• Description: Curcumin is a well-known active ingredient from turmeric with potent anti-inflammatory and antioxidant effects. Agile Smart Health Technology offers high-purity curcumin for use in pharmaceuticals, functional foods, and cosmetics.
• Key Applications:
o Anti-inflammatory drugs and supplements.
o Skincare products for anti-aging and skin-brightening.
o Functional foods and beverages. - Berberine
• Description: Extracted from various plants like Berberis, berberine supports metabolic health and has antimicrobial properties. Available in high-purity form for pharmaceutical and nutraceutical use.
• Key Applications:
o Blood sugar management and metabolic health supplements.
o Antimicrobial agents in natural health products. - Thymol
• Description: A natural monoterpene phenol derived from thyme oil, thymol is known for its antimicrobial and antiseptic properties, making it a valuable ingredient in pharmaceuticals and cosmetics.
• Key Applications:
o Oral care products such as mouthwashes.
o Antimicrobial formulations in skincare. - Menthol
• Description: Menthol, derived from peppermint oil, is widely used for its cooling and soothing properties. It is available in both natural and synthetic forms for various industrial applications.
• Key Applications:
o Topical analgesics and decongestants.
o Flavors for food, beverages, and oral care. - Concrete and Absolute Extracts
• Description: These highly concentrated plant extracts are used in perfumery, cosmetics, and high-end aromatherapy products. Known for their rich fragrance and therapeutic properties.
• Key Applications:
o Luxury perfumes and natural cosmetic formulations.
o Aromatherapy blends.
Target MCrocinarkets:
- Pharmaceutical Industry:
o Target companies producing natural and synthetic drug formulations focusing on chronic disease management, such as inflammation, metabolic disorders, and mental health. - Functional Food & Beverage Industry:
o Collaborate with manufacturers of health-oriented products like herbal teas, fortified beverages, and dietary supplements. - Cosmetic Industry:
o Focus on natural cosmetics and skincare brands looking for high-quality active ingredients for anti-aging, moisturizing, and soothing products. - Nutraceuticals:
o Position your extracts as premium ingredients for dietary supplements addressing stress, metabolic health, and immunity.
Product Range:
- Essential Oils:
o Types: Fruity, natural, and heat-resistant.
o Applications: Used in perfumes, food flavoring, aromatherapy, and skincare products. - Plant Extracts:
o Forms: Aqueous, alcoholic, and hydroalcoholic (available in liquid and powder).
o Applications: Functional food ingredients, medicinal supplements, and cosmetic formulations. - Plant Active Ingredients:
o Purity Levels: Customizable to meet specific industry standards.
o Use Cases: Key components in drugs, food supplements, and cosmetic actives. - Pure Crocin & Saffron Extract:
o Crocin: Known for its antioxidant and anti-inflammatory properties, widely used in the pharmaceutical and functional food sectors.
o Saffron Extract: Valued for its therapeutic properties and flavoring qualities in high-end cosmetic and food products. - Active Pharmaceutical Ingredients (APIs):
o Berberine, Curcumin, Conceret Vital for drug formulation, ensuring quality, safety, and efficacy. - Nano-Encapsulation:
o Purpose: Improves bioavailability and stability of active compounds.
o Applications: Advanced drug delivery, functional foods, and enhanced cosmetic formulations.
Services:
- Consulting Services:
o Pharmaceutical Industry: Assistance in creating innovative, effective formulations.
o Food Industry: Development of health-oriented functional foods.
o Cosmetic Industry: Crafting natural and efficient cosmetic products. - Formulation of New Products:
o From concept to market-ready products, tailored for specific market demands. - Specialized Sensory Evaluation:
o Conducting tests to assess the sensory attributes of products, ensuring consumer satisfaction. - Training Services:
o Providing necessary knowledge and skills in formulation techniques and sensory analysis.
This comprehensive offering positions your company as a key player in advancing product innovation and supporting customers in bringing high-quality, natural products to the market.
The formulation of new products using niosomes and liposomes for encapsulating herbal active pharmaceutical ingredients (APIs) is an advanced technique in the pharmaceutical, food, and cosmetic industries, primarily for improving the stability, bioavailability, and targeted delivery of active compounds. Both niosomes and liposomes are types of vesicular systems that can encapsulate herbal APIs, enhancing their performance and effectiveness.
- Niosomes (Non-Ionic Surfactant Vesicles)
Niosomes are vesicles formed by non-ionic surfactants and are similar to liposomes, but instead of phospholipids, niosomes are composed of surfactant molecules, cholesterol, and possibly other excipients. Niosomes are widely used for encapsulation because they offer several advantages, including cost-effectiveness and stability.
• Advantages of Niosomes for Encapsulation:
o Stability: Niosomes tend to be more stable than liposomes, particularly in acidic or high-temperature conditions.
o Cost-Effective: Since they use non-ionic surfactants (which are generally less expensive than phospholipids), niosomes offer a more affordable option for large-scale production.
o Improved Bioavailability: Niosomes enhance the solubility and absorption of poorly water-soluble herbal APIs, increasing their bioavailability.
o Controlled Release: Niosomes provide controlled or sustained release of the encapsulated herbal compounds, reducing the frequency of administration.
o Targeted Delivery: The size and surface charge of niosomes can be modified to target specific tissues or organs, improving therapeutic outcomes.
• Commonly Encapsulated Herbal APIs:
o Curcumin: An antioxidant from turmeric with potential anti-inflammatory properties.
o Crocin: Extracted from saffron, used for antidepressant.
o Ginseng Extract: Known for enhancing energy and immune function.
o Concerete & Absolute: Extract from natural Rose for cosmetic products.
Niosome Formulation Process:
• Preparation: Typically involves the hydration of a dry lipid film made from surfactants and cholesterol, followed by incorporation of the herbal API.
• Characterization: Size, zeta potential, entrapment efficiency, and release profiles are crucial parameters. - Liposomes
Liposomes are spherical vesicles composed of phospholipids (and sometimes cholesterol), designed to encapsulate active ingredients. They are well-known for their ability to carry both hydrophilic (water-soluble) and lipophilic (fat-soluble) compounds, making them ideal for encapsulating a wide range of herbal APIs.
• Advantages of Liposomes for Encapsulation:
o Biocompatibility: Phospholipids used in liposomes are naturally occurring in cell membranes, making them highly biocompatible and less toxic.
o Enhanced Drug Delivery: Liposomes can deliver herbal compounds to specific sites in the body (like tumors or inflamed areas) with higher precision.
o Improved Absorption: Liposomes enhance the solubility and absorption of both hydrophilic and lipophilic herbal APIs.
o Sustained Release: Similar to niosomes, liposomes can be designed for controlled release, improving therapeutic efficacy and minimizing side effects.
Liposome Formulation Process:
• Preparation: Liposomes are typically prepared using techniques like thin-film hydration or reverse-phase evaporation. The herbal API is incorporated into the lipid layer or the aqueous core of the liposome.
• Characterization: Key properties like size, encapsulation efficiency, stability, and release kinetics are assessed to ensure the desired therapeutic effect.
Benefits of Using Niosomes and Liposomes for Encapsulating Herbal APIs:
- Improved Stability: Both methods improve the stability of herbal APIs, protecting them from degradation due to factors like light, heat, or oxidation.
- Enhanced Bioavailability: Many herbal APIs suffer from low bioavailability due to poor water solubility. Encapsulation in niosomes or liposomes improves the solubility and absorption of these compounds in the gastrointestinal tract.
- Targeted Delivery: Liposomes, in particular, can be modified with targeting ligands to deliver herbal APIs specifically to target organs, tissues, or cells, which is especially useful for pharmaceutical and cosmetic applications.
- Controlled and Sustained Release: Both niosomes and liposomes can be engineered to release their payload slowly over time, providing prolonged therapeutic effects and reducing the need for frequent doses.
- Non-Toxicity: Niosomes and liposomes, when prepared correctly, are non-toxic and biocompatible, which is essential for formulating natural products like herbal APIs for human use.
Applications in Different Industries:
- Pharmaceutical Industry:
o Formulation of Herbal-Based Drugs: Niosomes and liposomes can be used to deliver herbal APIs more effectively in various drug forms, including oral tablets, injectables, or topical formulations.
o Enhanced Drug Delivery: For poorly soluble drugs, herbal APIs encapsulated in liposomes or niosomes show improved pharmacokinetics. - Functional Food:
o Bioactive Ingredients: Encapsulating herbal compounds (e.g., curcumin, ginseng extract, Berberin, thymol, menthol, crocin,safranal) in liposomes or niosomes can enhance their bioavailability and make functional foods more effective in promoting health benefits. - Cosmetic Industry:
o Anti-Aging and Skin Care: Herbal extracts like resveratrol or green tea extract can be encapsulated for sustained release and better absorption in skincare formulations.
o Targeted Skin Delivery: Liposomal encapsulation allows the targeted delivery of herbal compounds to specific skin layers, enhancing efficacy in treating skin conditions.
By incorporating niosomes and liposomes into the formulation of herbal APIs, your company can offer more effective, stable, and bioavailable products that meet the growing demand for advanced natural therapies in pharmaceuticals, functional foods, and cosmetics.
